Social media outreach brought in hundreds of interested patients. The site could not handle this volume, so nRollmed rigorously pre-screened all interested patients and referred only those who were well-qualified to the site. • nRollmed employed other innovative strategies to bring in patients such as advertising in WhatsApp groups for audiences that traditionally do not use the internet, approaching nurses and community doctors, and collaborating with online influencers and the National Diabetes Association. • To save the site and patients’ time, nRollmed had patients securely send a photo of their ulcer to the site to assess if a screening visit was warranted. • nRollmed recommended that the sponsor reconsider several stringent criteria. This led to a protocol amendment, allowing more potential patients to screen. • nRollmed developed a deep understanding of the patient population and the study’s criteria, which enabled ongoing optimization of the advertising and prescreening strategy. • nRollmed developed a close relationship with the study coordinator, which enabled troubleshooting, increased commitment, and allowed nRollmed to step in without delay to help the site reach and follow up with patients. • nRollmed periodically checked in with patients who didn’t qualify but had the potential to in the future, such as someone with an active infection in the ulcer, or someone with an ulcer that was too “new” to meet the inclusion criteria.
